How to Appeal a Medication Denial: Ozempic, Wegovy, Zepbound & Mounjaro
Had your GLP-1 medication denied? You're not alone. According to ENDO 2024 research,64% of GLP-1 prescriptions are denied for patients with obesity. This guide shows you how to appeal and get the medication you need.
Key Statistics: GLP-1 Medication Denials
- 64% denied — GLP-1 prescriptions for obesity-only patients (Endocrine Society ENDO 2024)
- 32% denied — GLP-1 prescriptions for type 2 diabetes patients (ENDO 2024)
- 39-59% appeal success — Internal appeals that succeed when properly documented (CNN Health)
- 85% never appeal — Despite high success rates when they do (CNN Health)
GLP-1 Medications and Insurance Coverage
| Medication | FDA Approved For | Monthly Cost | Insurance Coverage |
|---|---|---|---|
| Ozempic | Type 2 diabetes | $968 | Usually covered for diabetes |
| Wegovy | Weight loss, cardiovascular | $1,349 | Mixed — many denials |
| Mounjaro | Type 2 diabetes | $1,069 | Usually covered for diabetes |
| Zepbound | Weight loss | $1,060 | Mixed — many denials |
Why GLP-1 Medications Get Denied
Weight Loss Plan Exclusion
Many employer plans explicitly exclude "weight loss drugs" or "treatment of obesity." According to KFF research, only ~25% of employers covered GLP-1s for weight loss in 2023.
Step Therapy Requirements
Insurers require trying cheaper medications first (like metformin or phentermine) before approving GLP-1s. Document failed prior treatments.
BMI Thresholds Not Met
Many plans require BMI ≥35 or ≥30 with comorbidities. Some have increased thresholds to reduce approvals.
Missing Documentation
Lack of documented lifestyle modifications, weight history, or physician-supervised diet attempts.
"Not Medically Necessary"
Insurers argue obesity is a "lifestyle choice" despite FDA approval and clinical guidelines supporting these medications.
Good News: Wegovy Cardiovascular Approval (March 2024)
According to the FDA, Wegovy received approval in March 2024 for reducing cardiovascular risk (heart attacks and strokes) by 20% and death by 19%.
This approval may improve coverage for patients with heart disease and BMI ≥27. If you have cardiovascular risk factors, cite this approval in your appeal.
Step-by-Step: How to Appeal a Medication Denial
Document Medical Necessity
Work with your doctor to document your BMI history, weight-related health conditions (diabetes, hypertension, sleep apnea, heart disease), and previous weight loss attempts that failed.
Get a Letter of Medical Necessity
Ask your doctor to write a detailed letter explaining why this specific medication is necessary for your condition, why alternatives won't work, and citing clinical guidelines and FDA approval.
Document Failed Prior Treatments
If step therapy is required, document all previous medications and why they failed (side effects, lack of efficacy, contraindications). Include records of supervised diet programs.
Cite Clinical Guidelines and FDA Approval
Reference FDA approval, American Association of Clinical Endocrinology (AACE) guidelines, and American Diabetes Association (ADA) recommendations.
Submit Your Appeal Before the Deadline
According to HealthCare.gov, most plans require appeals within 180 days. Send via certified mail and keep copies.
Sample GLP-1 Medication Appeal Letter
Frequently Asked Questions: Medication Denials
What is the denial rate for GLP-1 medications?
According to ENDO 2024 research,64% of GLP-1 prescriptions for patients with obesity only are denied. The rate drops to 32% for patients with type 2 diabetes.
Do medication appeals work?
Yes. According to CNN Health, internal appeals succeed 39-59% of the time when properly documented. However, 85% of people never appeal.
Does Medicare cover weight loss drugs?
Currently, Medicare is explicitly banned from covering weight loss drugs (since 2003). However, the NAIC notes that advocacy efforts are ongoing to change this policy.
What if my plan has a weight loss exclusion?
If your plan explicitly excludes weight loss treatment, appeals typically won't work. However, if you have type 2 diabetes, the medication may be covered under diabetes treatment. Check with your employer's HR department about plan changes.
Related Appeal Guides
About This Guide
This guide is provided for educational purposes only and does not constitute medical or legal advice. Statistics cited are from publicly available sources including the Endocrine Society, CNN Health, and NAIC.
Always work with your healthcare provider to determine the best treatment options for your condition.